GEMINI

Maternal Interaction With Gametes and Embryo

COST Action FA0702

Objectives

 

The main objective of the Action is to establish a network of European researchers working on different aspects of maternal interaction with gametes and embryo in different species to advance towards creation of a so called “Interactome” map of cell-to-cell interactions as well as endo- and paracrine interactions between gametes, embryos and female reproductive tract during different stages of reproductive cycle and pregnancy at health and under disturbed maternal nutrition and metabolism.

We hope to achieve the above objectives by realising the following specific goals:

I) To establish the optimum in vivo model(s) for creation of an interactome map/database of maternal interaction/communication with gametes and embryos.

II) To establish the optimum currently available in vitro model(s) for creation of an interactome map/database of maternal interaction/communication with gametes and embryos and to establish strategies for progress from in vivo towards in vitro models for creation of the interactome map.

III) To establish guidelines and standards for the use of in vivo and in vitro models in investigation of the effect of maternal interaction/communication with gametes and embryos allowing
investigators in different European labs to share data and information.

IV) To increase knowledge regarding tools and technologies used for characterization of maternal interaction/communication with gametes and embryos.

V) To increase our knowledge base regarding application of “Systems Biology” approaches in the understanding of maternal interactions/communications with gametes and embryos.

VI) To develop methods and tools for translation of knowledge gained from the interactome map into improved protocols for the European Animal Breeding and Biotechnology industry.

VII) To establish guidelines and standards for investigating the effect of disturbed maternal nutrition on maternal interaction/communication with gametes and embryos allowing investigators in different European laboratories to share data and information.